Advanced Healing Arts Med Center: Walter Mark V MDRead More
Do you have joint pain, back pain, neck pain or some other orthopedic problem or injury that is not getting better? Are you interested in leading-edge technology that can heal most orthopedic and musculoskeletal problems faster and better than standard approaches and avoid the need for surgery?
Welcome to the exciting new field of Stem Cell Orthopedics! Stem Cells and Regenerative Medicine are poised to revolutionize almost every field of medicine. The answer to degenerative disease is regenerative medicine.
Stem cells are the way the body regenerates. We have stem cells all over our body constantly rebuilding and repairing tissues. If we didn’t have stem cells we would die in a short amount of time.
At times the body’s capacity to regenerate is overwhelmed and that’s when people degenerate. The very best way to fix it is to take the persons own stem cells, boost them as necessary with growth factors from their blood and use this tool to fix whatever the problem is.
We now have the technology to use your own stem cells to heal many common orthopedic problems faster and better than surgery. With a single treatment we have a better than 80% success rate with problems such as Osteoarthritis of the knee or hip (even bone-on-bone), Rotator cuff, chronic back pain, sports injuries and many other conditions. The whole treatment is done in about 4 hours at our state-of-the-art facility and is minimally invasive and very safe.
Since abdominal fat is by far the most plentiful source of mesenchymal stem cells (far more than in bone marrow) we only use stem cells from the patient’s own fat. We gently collect about 60-120 cc’s of belly fat with a mini-liposculpting procedure done in our very own offices. We then isolate the stem cells and mix them with growth factors from your blood. The stem cells are then injected in just the right spots to regenerate and heal the affected joint(s) and surrounding ligaments and tendons.
We can’t really predict how fast patients will see improvement but it is not uncommon to see quite dramatic results even within a week or two. The stem cells will remain alive for several months and patients will continue to build new tissue and heal for that period. Once the structures are rebuilt there is every reason to believe that the improvements should be long-lasting.
There is very little downtime after a treatment. Patients will generally be a little sore for a few days but should be able to resume normal activities very quickly
STEM CELLS are the medicine of the future. When properly prepared and applied, stem cells can achieve some pretty amazing results. Please visit our video/testimonial page to see some patient success stories.
34239
33143
Your search for the top insurance agency in Maitland, FL, ends with Mike Elliott Insurance Agency, Inc. For more details visit our site now.
Want to enhance your feet by performing foot surgery without getting any complications, then you are at the right place. Dr.Ray Lopez is known for his techniques in minimally invasive foot and ankle surgery. His only mission is to deliver his patients the highest level of care with the greatest results.
33140
Autologous Conditioned Plasma (ACP) aka PRP has numerous corrective pain management indications for patients that are non-responsive to conventional treatments. ACP injections have been utilized with a number of medical conditions including tendinopothies, joint pain, arthritis, and sports medicine applications. In this 1-Day course you will receive extensive training in the harvesting and administration of ACP including the use of biologics (concentrated growth factors) such as amniotic tissue as well as stem cells derived from adipose cells for use in patients. Enhance patient care and realize the benefits of using and offering these regenerative therapies within your practice and create new revenue streams and greater patient satisfaction.
This evidence based course will prepare attendees to diagnose, harvest, and administer these regenerative therapies in an office setting. These interventional procedures can be performed safely within an office setting (clean procedure | aseptic procedure) and can be used in combination with conventional treatments without complications and to the benefits of patients. Autologous Conditioned Plasma (PRP) can be used as a stand-alone treatment effectively or combined with Allograft CGF (Concentrated Growth Factors) to compliment traditional pain management therapies. Typically, ACP injections are cash basis procedures and the average cost to patients is approximately $600 - $800 per injection cycle (before biologics) or treatment in pain management applications.
Included in the course study will be concentrated growth factors to enhance your ACP injections using allograft concentrated growth factors and stem cells from amniotic tissue or bovine (A-Cell). Anecdotal studies and peer to peer cite reviews show increased biological activity, accelerated healing, and correction when used in combination with ACP. All attendees will receive complete injection protocols, standard of care, and complete information on the procedures to diagnose and gauge improvement of these conditions for treatment.
Common medical uses and indications for the use of ACP and Allograft CGF (Concentrated Growth Factors) include:
Shoulder Area
Rotator Cuff (Partial Tear)
Biceps Tendinosis
Glenohumeral Ligament Sprains
Shoulder Joint (Arthritis Pain)
Elbow Area
Lateral Epicondylitis
Distal Biceps Tendon (Partial Tear)
Elbow Joint (Arthritis Pain)
Hand Area
Chronic Thumb UCL Sprain
Small Digit Injections (Arthritis Pain)
Knee Area
Patellar Tendinosis
Meniscal Tears (Partial Tear)
Vastus Lateral Oblique Strains (Chronic)
Osgood-Schlatters
Knee Joint (Arthritis | Cartilage Regeneration)
Spinal Area
Para-Spinal Muscles (Failed Back Surgery)
SI Joint Injections (Increased Vascularity)
Ankle | Foot Area
Chronic ATF Ligament Strains
Chronic Achilles Tendinosis
Chronic Peroneal Tendon Tears
Plantar Fasciitis
Other Medical Conditions
Diabetic Neuropathies (Lower Extremities – Ischemic)
Carpal Tunnel Syndrome (Scar Tissue)
Jones Fracture (Accelerated Healing | Vascular)
Muscle Atrophies and other soft tissues.
As part of the course study you will be introduced to the various stem cell therapies also being performed in conjunction with ACP or conventional medicine. The growth in using mesenchymal cell therapies is expanding beyond orthopedic offices and the demand from patients is becoming popular. These experimental therapies are being used successfully globally and within the United States but do have additional limitations as these are not FDA-Approved and its uses are limited to orthopedic conditions for larger joint pain. Adipose Stem Cells (ASC) and Bone Marrow Stem Cells (BMAC) are the available options for physicians but there are no professional medical guidelines for who can and cannot receive stem cell therapy. Stem Cell Therapies are considered to be experimental by the FDA so the decision about who gets stem cell therapy is up to patients and doctors and there are legal requirements as to the advertisement of such within your practice.
The Adipose Stem Cell Therapies (ASC) and Bone Marrow Stem Cells (BMAC) procedures include all protocols for harvesting and re-injection, patient selection criteria, contraindications, and expected results for the most common types of arthritis to the knee and shoulder areas. Candidates for such treatment are usually mild to moderate degeneration of capsule and the most robust response to these treatments are candidates that are younger to middle age and in good medical health. There are other experimental uses of mesenchymal cell therapies such as Multiple Sclerosis and Alzheimer’s though the course will concentrates only in the pain management application therapies.
Empire Medical Training will prepare you to integrate these new procedures within your practice and apply the latest standard of care considerations to be able to perform these safe and effective nonsurgical procedures. We provide a large amount of supplemental data for review after the course and attendees will receive complete protocols for all the procedures associated with the ACP (Autologous Conditioned Plasma), Allograft CGF (Concentrated Growth Factors), and Stem Cell Therapies being employed with sports medicine, orthopedic offices, hospitals, and private practice. Marketing, pricing and packaging, and detailed pre and post-treatment options for patients are given as well as the legal, ethical, and administrative concerns associated with the introduction of these new procedures.
Give your patient the latest treatment options for pain, enhance patient care in the management of various pain conditions presented, and differentiate yourself from others with these expanded pain management procedures. The additional revenue streams associated with these procedures are attractive to physicians and are the perfect addition to any medical practice treating these various chronic soft tissue and joint related arthritis conditions.
Objectives for the ACP (Autologous Conditioned Plasma) and Stem Cell Therapies for Pain Management
Understand and evaluate the latest in Pain Management procedures concerning ACP and stem cell therapies for the treatment of chronic and sub-acute pain indications including soft tissue pain (tendinopothies) and joint pain as a stand-alone treatment or in combination with conventional treatments.
Learn the principles and gain a working knowledge of the various systems and products available for the mechanical harvesting of concentrated blood platelets, adipose cells, and bone marrow aspirate. Secondary system considerations are given to the purification and concentration of the adipose cells and BMAC. You will also learn and understand the various Allograft Concentrated Growth Factor commercial products available associated with ACP including amniotic tissue products and bovine products available.
Learn the various types of specific medical conditions that can be successfully treated with ACP, CGF, and stem cell therapies including detailed protocols, injection diagrams, diagnostic tools, and standard of care considerations. Introduction of alternative treatments such as Umbilical Cord Blood products for specific indications.
Receive and understand the business aspects of inclusion of these new procedures including liability (malpractice) insurance, promotion limitations, FDA opinion, and administration issues (i.e. consents, intake forms, etc.) associated with these new pain procedures.
Understand which procedures can be used in combination with conventional pain management therapies; global period, contraindications, and patient expectations for the various anatomical pain presentations as well as the need for additional treatments.
Learn which steps to complete to be successful concerning pre-treatment, technologies, consultation, the actual procedure, and post procedure imaging and possible further correction of pain modalities.
Access and enduring materials for all of the various injections, functional orthopedic exams for differential diagnosis, and detailed diagrams and protocols for the various injections and expected outcomes or degree of improvement expected for patients.
As with all of the courses offered by Empire Medical Training, we wish for you to be successful with the integration these concepts and methodologies so you become financially successful with these new pain management procedures. For those physicians wishing to do so, additional preceptorship training and consultation is made available as an option in addition to the course as well as supplemental schedules contained within the physician portal.
33306
Welcome to EternaM.D.
The Science of Beauty
Eterna M.D. Mission Statement
At Eterna M.D. Medical Rejuvenation Center, We believe in the possibilities of improving your physical appearance while at the same time becoming a healthier person are endless. Our mission first and foremost if to help people.
EternaMD integrates health and beauty, because we believe beauty cannot exist without health.
There are three phases to your Eterna M.D. experience:
A comprehensive medial evaluation to determine your needs.
Your personalized treatment plan.
The results obtained after each treatment, where what was imagined becomes visible to the eyes.
Featured Rejuvenating Treatments
Where Age Becomes Youth
Are you ready to escape to a place of peace, health, and overall true well-being? Experience one of our many rejuvenating medical spa treatments to revitalize not only your appearance, but also your spirit. Read about our professional treatments and step into the next generation at EternaM.D.. Whether you are looking for a one-time quick fix-me-up, or a custom-made treatment plan, we are here to meet your desires. From Liposculpture to Injectables, our medical spa offers just about everything to take you back years!
32746
Heal naturally - Use your own stem cells.
At Florida Stem Cell, it is our priority to provide you with options that use your body’s healing mechanism to rebuild and repair your joints utilizing your stem cells.
Introducing a new and better way to heal joints.
Stem Cell Therapy for Arthritis, Injuries & Joint Pain.
Do you have joint pain, back pain, neck pain or some other orthopedic problem or injury that is not getting better?
Are you interested in new technology that can heal most orthopedic and musculoskeletal problems faster and better than standard approaches, without the need of surgery?
At Florida Stem Cell we specialize in rebuilding joint, back and neck structures using a person’s own stem cells. Stem cells are like little workers that can regrow cartilage, ligaments, tendons and even bone. By taking some fat in a simple outpatient procedure, separating out the stem cells and then mixing them with some growth factors (PRP) from a small blood draw we have a powerful tool to rebuild almost any joint in the body.
A dedicated team just for you.
At Florida Stem Cell, we are a dedicated team of 6 Physicians and 2 Scientists who specialize in Stem Cell and PRP Therapies. Our team also consists of Physician Assistants, Nurses, Medical Assistants, Phlebotomist, Lab Manager and other affiliate physicians who work with us. We strive to routinely participate in continued education and research to stay abreast of the most current medical opportunities in the field of Stem Cell and Anti-aging Therapies.
It is our priority to ensure that every procedure is safe, convenient and implemented using only the highest standards and protocols. Our success is unmatched due to our unique technology that yield high viability counts because we do not utilize a stem cell kit.
The Florida Stem Cell Medical facility provides a safe, comfortable and embracing environment.
32080
Foot & Ankle Institute of Miami Beach offers the latest in advanced stem cell and blood platelet procedures for foot and ankle conditions. Before you consider ankle surgery, fusion or replacement, consider the world’s leading cell-based therapy and prp injection treatments to help alleviate pain with a non-surgical injection procedure.
Stem cell therapy has made captions in the medical field in recent years in United States. Many people have sought stem cell therapy in other countries as an option for non-surgical management of injuries and conditions. Various types of stem cells are utilized by our team of physicians at the Foot & Ankle Institute of Miami Beach. Each physician is an expert in their field and will recommend the appropriate cell-based therapy procedure during your one-on-one consultation.
How does cell-based therapy work?
Stem cell treatment takes advantage of the body’s ability to repair itself. These stem cells have anti-inflammatory properties, similar to cortisone and steroid shots. However, stem cell therapy goes far beyond the benefits of standard “injection therapy. Cell-based therapy treats orthopedic joints and injuries, muscular injuries, wounds, ligament injuries, arthritis, back pain, along with reversing anti-aging and cosmetic enhancement.
While cortisone and other drugs only provide temporary pain relief, stem cells actually restore degenerated tissue while providing pain relief. The list below represents the most commonly treated foot and ankle conditions using restorative cell-based therapy. This is not a complete list, so please contact our office to learn more about conditions treated.
PLATELET RICH PLASMA THERAPY – (PRP)
Foot & Ankle Institute of Miami Beach treats hundreds of patients with injuries of the foot and ankle with Platelet Rich Plasma Therapy (PRP) with proven results. Patients travel from all over the globe to receive PRP therapy to aid in their recovery and expedite healing of surgical wounds and injuries. Dr. Allison Guyen, FACFAS is the leading regenerative physician specialized in PRP therapy and Stem Cell therapy. Dr. Guyen has lectured nationally and internationally on her experiences with regenerative medicine for many years.
There has been much attraction and medical media about PRP in the last several years and its proposed indications. Many celebrities and professional athletes have received PRP for various problems and chronic conditions thus allowing the exposure of this science to the general mass population. This is one modality that is considered as a non-surgical open approach to aide in healing of acute tendon ligament injuries, muscle injuries, adjunct to certain surgical procedures, arthritis, fractures, wounds, and cosmetic.
What is Platelet Rich Plasma? (PRP)
Platelet-rich plasma is a blood component that has been enriched with platelets. The PRP contains rich in autologous growth factors and cytokines that can help stimulate healing of bone and soft tissue in the body.
Platelets are an integral part of your blood that contains a high concentration of bioactive proteins, especially growth factors, that initiate a signal conduction cascade, which in turn stimulates your body’s natural healing process in order to repair damaged tissue. Platelet Rich Plasma or PRP treatment is your body’s natural healing process, however much more concentrated.
The concept of this treatment is that PRP not only stimulates but also aids the body’s natural healing response of damaged tissue. PRP accelerates the process of recruitment of necessary bioactive proteins to the damaged area and allows for the creation and maturation of collagen fibers to strengthen the tendons and ligament of the damaged site.
33140
Global Stem Cells Group
Brings leadership in stem cell research, patient applications, and training to you through our state-of-the-art global network of companies. Our mission is to enable physicians to make the benefits of stem cell medicine a reality for patients around the world.
Global Stem Cells Group’s mission is to become the world leader in adult stem cell therapies and physician training in stem cell protocols and medical procedures and provide superior regenerative medicine products and supplies to the medical community. Our synergistic strategy positions us on the leading edge of stem cell research, physician education and patient care. The Global Stem Cells Group is the parent company of six, wholly-owned operating companies, each administering to specific areas related to the stem cell industry.
These companies provide research, education, tools, and medical procedures to physicians and patients interested in the many benefits of stem cell therapies. Founded in 2012, the company began as patient advocacy and medical treatment platform to form a key part of the company’s overall strategy. The founder, Mr. Benito Novas leads the company as CEO. He is also the majority stockholder, and actively manages the day-to-day operations of the company. The Corporate headquarters for the Global Stem Cells Group is in Miami, Florida.
The Global Stem Cells Group is a stand out from many companies in the stem cell medicine arena in that we focus on serving our clients by delivering the most relevant cutting edge solutions. We are committed to balancing competitive pricing and providing solid economic gains for our shareholders. By providing the best cellular medicine services available, we believe that we are building a company that will create more value for our customers and our stockholders.
We pledge to adhere to the highest standards of integrity on behalf of our customers, our stockholders, and the world. We have created the optimal corporate structure to realize Global Stem Cell Group’s long-term potential, and we have established the appropriate financial controls and management oversight of our internal processes.
33016
Dr. Leon Mead is a Board Certified Orthopedic Surgeon who has been practicing in Naples, Florida for more than 20 years. He is Southwest Florida’s only dual Fellowship trained Orthopedic Surgeon in Joint Replacements and Sports Medicine. He has an inherent interest in Shoulder, Hip and Knee Surgery and has been a pioneer in the exciting realm of minimally invasive joint replacement surgery and all arthroscopic rotator cuff repairs.
He was a graduate of Wayne State Medical School in Detroit, completed his Residency at The University of Texas at Houston, and Fellowship trained at the prestigious Institute for Bone and Joint Disorders in Phoenix, Arizona. More recently he was admitted to The Society for Arthritic Joint Surgery and earned a Subspecialty Certification in Sports Medicine by the American Board of Orthopedic Surgery.
Stem Cells Therapy
If you are unfortunate enough to have arthritis, now is a particularly exciting time, because there are now options that have not been previously available that may actually halt or reverse your arthritis. Below I have summarized all options currently available. They fit into several categories: Holistic, Bandaids, Surgery, and Biologics.
We will start with the holistic category. This group will include all nontraditional forms of treatment. As a whole, there is no data to support their use. This would include glucosamine and chondroitin, cherry juice, prolotherapy, copper and/or magnetic bracelets, and a whole host of other options. This certainly includes the “Miracle Cures” that seem to run rampant in all forms of advertising these days.
While all of these are unlikely to be harmful, they really don’t do much for most patients. Our Academy of Orthopaedic Surgeons actually recommends against the use of chondroitin/glucosamine because all the studies to date have been done by the manufacturers and after 15 years, there is still no data to support its use.
Glucosamine/Chondroitin does make some people feel better because there is a mild anti-inflammatory effect that occurs with use. None of these options can halt or reverse arthritis. Personally, I don’t have strong feelings one way or the other about using these options. If you feel better on them, that’s fine. Just don’t expect much if you decide to use these, and certainly, don’t ignore proven treatments.
—
The second group is the Bandaid group. This includes all traditional forms of treatment and includes bracing, cortisone and gel injections, anti-inflammatory medications, and Physical Therapy. All of these can help with the symptoms of arthritis, but do nothing to alter the progressive deterioration of the joint. Think of cold tablets when you have a cold. They help with some of the symptoms, but don’t make you feel great and certainly don’t shorten the disease. As opposed to holistic options, these have all been proven in a multitude of well-designed studies to help control the symptoms of arthritis. Implicit in their use is that one is merely waiting until the symptoms worsen and then either live with significant limitation or undergo replacement surgery. In general, these options can provide moderate, but not excellent relief of symptoms. Unlike the holistic group, there are documented potential damaging side effects with most of these options. This doesn’t mean they are less safe than holistic options. It means they have undergone the intense study and scrutiny that none of the holistic options have.
Bracing is probably the least helpful of these options, but there is no downside to their use. Most people with arthritic knees will find that a neoprene sleeve makes the knee feel a little better. More rigid unloader type braces can provide some relief during vigorous activity but are too bulky and uncomfortable to be worn full time.
Cortisone shots can provide reasonable short term relief for an inflamed knee and are frequently the first option many people with arthritis choose. The first shot not infrequently will last several months, but repeat injections end up helping only a few weeks. These shots can be repeated every 34 months as needed. This typically is not a good long term strategy because it ceases to be effective. The cortisone also is detrimental to joint health and actually has been shown to be toxic to chondrocytes, the living cell in joint cartilage.
Gel injections are composed of hyaluronic acid, the same compound that is present in human synovial fluid. The theory behind these injections is that in arthritic knees, the molecular weight of the hyaluronic acid decreases, and by adding a larger molecule, the shock-absorbing capability increases. It’s not clear how these shots help because they have been shown in radioactive labeling studies to be no longer in the knee 48 hours after injection. Typically these injections are given in a series, one a week for 3 weeks. Gel One and Synvisc One are single injections. The series can be repeated every 6 months. These injections are intended for and work best in knees that have at least 50% of the joint space remaining on weight-bearing films. They work least well when bone on bone findings are present. Numerous studies have shown that the gel injections are no more helpful than cortisone injections, but they do not harm the articular surface like cortisone. Unlike cortisone, 10-20% of the patients may develop an adverse reaction to the gel injections and experience severe pain and swelling within 72 hours of the injection. When this occurs, the patient may not have any more of these injections. These are expensive injections and Blue Cross will no longer reimburse for them. Medicare requires at least 3 months of prior treatment before they will authorize these injections.
Anti-inflammatory medications are the most common treatment for arthritis. They all work by inhibiting the formation of cyclooxygenase 1 and 2 which are precursor molecules in the inflammatory cascade. These medications do not alter the progressive deterioration that is the hallmark of osteoarthritis but can help with some of the symptoms of swelling, warmth, and pain. As arthritis progresses, these medications tend to helpless and less. I liken them to cold medication, cold medications can make you feel some better, not great, but cannot shorten the duration of the cold. A significant problem with these medications is that heart attack and stroke are associated with their use and can occur early in the treatment course. The risk of this remains relatively low, however. Also, many people do not tolerate these medications because of stomach upset, and ulcer formation is a concern.
Physical therapy can help to improve muscular strength and endurance as well as improve the range of motion. This is most helpful when significant muscle atrophy is present. This is almost always is used in conjunction with other treatment options. The degree of joint deterioration usually limits the effectiveness of therapy to significantly improve muscle tone. Non Impact activities such as upright biking, Precor machines, and aquatic exercise can minimize joint irritation while helping to increases muscle tone. Again, this option does nothing to alter the progression of arthritis.
—
The third option is surgery. This group includes arthroscopic surgery and joint replacement. Generally speaking, arthroscopy is reserved for joints with meniscal tears and little arthritis. Because arthritis is a loss of the joint surface with secondary inflammation and not something extra in the joint causing problems, it cannot be removed arthroscopically. For patients with x-ray evidence of bone on bone contact in the joint, joint replacement remains the most definitive and predictable solution.
There have been over 40 years of joint replacement experience and while outcomes continue to improve, complication rates remain low. In a Medicare aged patient, it would be unusual to outlive the lifespan of the prosthesis.
The fourth option is the use of Biologics. Biologics are the only group that has the potential to alter the course of arthritis, possibly delaying or eliminating the need for a joint replacement. These options are considered investigational by third-party payers and are not covered by Medicare or insurance. The patient pays directly for these treatment options. There are 3 biologic options at this time, ACP, PRP, and Stem Cells. ACP stands for Autogenous Conditioned Plasma. This is obtained by drawing 15 ccs of blood from the patient and using a centrifuge to remove the cells, leaving 6 cc of plasma with growth factors. This is then injected into the affected joint. This has been shown to be as effective as the gel shots for patients with intermediate grades of arthritis. Because most cells are removed, it is the least biologically active of the three.
PRP or Platelet Rich Plasma is typically obtained by drawing 60 cc of the patient’s blood and centrifuging it to remove red and sometimes white blood cells leaving platelets and plasma. In order to qualify as PRP, the concentration of platelets should be at least 3x that of blood.
Platelets have alpha granules which produce multiple growth factors. There are multiple systems for the preparation of PRP with wide variations in platelet and white blood cell concentrations.
Accordingly, although it has been studied for nearly a decade, obtaining a consensus of outcomes has been difficult. There are, however, multiple studies demonstrating the superiority of PRP over cortisone and gel shots. PRP helps arthritis by turning off nearly 150 genes that have been turned on either by trauma or genetic programming. In an arthritic joint, the cartilage cells called chondrocytes produce toxic substances that cause a breakdown of the joint surfaces. The PRP temporarily turns these genes off, possibly slowing the progression of arthritis. No long term studies have been done to prove or disprove this concept. Studies also have shown that PRP with white blood cells doesn’t help arthritis as much as PRP without white blood cells. This is felt to be related to the inflammatory effect of white blood cells on the joint.
Stem Cells are the cells in our body that can potentially turn into any type of cell. These specialized cells have the unique capability of being able to regenerate damaged tissue. While the biology of the stem cell has been elucidated over several\ decades, only recently have we been able to harness their healing capabilities for musculoskeletal problems. This is because not all stem cells are able to regenerate joint tissues. Stem cells obtained from fat, for example, lack the growth factors necessary to reverse arthritis. Fortunately, recent advances have allowed us to painlessly harvest and concentrate stem cells from our bone marrow which has been proven to regenerate joint surfaces and increase meniscal volume. This can be done in a simple painless office procedure with a local anesthetic. Sixty cc’s of bone marrow is typically obtained from the iliac crest (hip bone) or upper tibia bone using the Biomac system. Obtaining bone marrow without this advanced equipment is typically painful. It is then filtrated and centrifuged to concentrate the stem cells for injection into the affected area.
As we age, our stem cells become less active. By adding growth factors to the stem cell injection, your older stem cells will behave more like juvenile stem cells and remain active for longer periods of time. These growth factors are obtained from a specific area in human placentas.
This tissue is called Amnion because it is obtained from the amniotic side of the placenta. The placentas are obtained from live healthy births from 12 hospitals in the Dallas area. There are no ethical concerns with this, as this tissue is discarded after the birth. All tissue is tested for disease and is sterilely processed. The FDA has approved this process. This tissue comes fresh frozen on dry ice and has to be used within 15 minutes of thawing to preserve the function of the growth factors. Within 7 minutes of exposure to these growth factors, adult non-active stem cells change their cellular characteristics and resemble the spindle-shaped juvenile more active form. These cells will then remain biologically active for up to 8 months, much longer than non exposed cells. Another huge benefit from the Amnion is that it inhibits scar tissue formation, allowing your body to heal with minimal scarring.
The stem cell functions in two ways. It can transform into the tissue that is damaged as well as coordinate healing. The best way to think of the stem is that of an orchestra conductor. Without the conductor, sound can be produced, but it would be disordered. This is analogous to scar tissue formation. Our body heals the injury with scar tissue. With a conductor, the sound is coordinated, not noise. The stem cell coordinates all the cells involved with healing to help regenerate the damaged tissue and minimize scar tissue formation. The true abilities of the stem cell was demonstrated in 1997 when Dolly the sheep was cloned from a single adult stem cell. Platelet-rich plasma has been used with some success for years and has been fairly extensively studied. There has been a limited success, however, in regenerating normal joint tissues with platelet-rich plasma. In this system, the platelet is just one part of the orchestra, not a soloist and healing is much improved.
Because this is an emerging and new technology, there are very few long term human studies to guide us. One study from Malaysia did demonstrate the ability to regenerate near-normal joint surface in damaged knees with stem cells. This was the first study ever to demonstrate synthesis of near-normal Type II collagen in the joint tissue that regenerated. Type II collagen is the main collagen found in healthy joint surfaces. Without stem cells, Type I collagen forms. This is the main collagen in scar tissue. Another study demonstrated an increase in meniscal (Knee cartilages) volume after meniscectomy. This is important because the meniscus is the main shock absorber in the knee. When it is damaged and removed, the joint surface sees increased stress (up to 275% increase) and subsequently degenerates. Any regeneration of meniscus will minimize the risk of developing arthritis.
In order to understand how stem cells can help prevent arthritis, it is important to understand a little about arthritis. Arthritis isn’t something that gets into the joint, but rather a loss of joint surface. Think of 30,000 miles on a tire with the steel belting showing through and you get an accurate picture of what arthritis is about. Arthritis begins when our joint cells, as a result of trauma or genetic programming, start producing compounds which breaks down the joint surface.
This genetic machinery can be turned off with stem cell treatment and halt the progressive damage to the joint surface. cuff healing with stem cell use. At six months from arthroscopic rotator cuff repair, the stem cell treated group had 100% of the cuffs intact on ultrasonic evaluation compared to only 67% of the non-stem cell group. At 10 years, 87% of the stem cell treated cuffs were intact, compared to only 44% in the non treated group.
Another study from France demonstrated superior rates of rotator cuff healing with stem cell use. At six months from arthroscopic rotator cuff repair, the stem cell treated group had 100% of the cuffs intact on ultrasonic evaluation compared to only 67% of the non-stem cell group. At 10 years, 87% of the stem cell treated cuffs were intact, compared to only 44% in the non treated group.
34102