WHY CHOOSE US?
At National Stem Cell Centers, our affiliated physicians are devoted to advancing safe, effective regenerative therapies such as stem cell treatment. Using sophisticated adult stem cell technologies, we are able to harvest adult mesenchymal stem cells (MSCs) from your own fat deposits, which are up to 2500 times more abundant than in bone marrow (Relevant research strongly suggests that stem cell treatment efficacy is related to the number of stem cells that can be recovered and deployed). After harvesting your stem cells on-site, we are able to reintroduce them, with a goal of stimulating a self-healing cascade.
Welcome to National Stem Cell Centers
At National Stem Cell Centers, our affiliate physicians focus on leading-edge, regenerative medicine. Instead of synthetic compounds, prescription medications, or surgical procedures, we activate your own natural cellular resources to promote healing.
Our goal is to allow patients access to this potentially revolutionary form of treatment to harness your body’s natural healing cascade mechanism for the repair of damaged tissues.
Adult mesenchymal stem cells are a form of undifferentiated cells. These kinds of stem cells are found in great abundance within fatty tissue. Lying dormant (non-replicating), these remarkably intelligent cells can be activated to become other kinds of cells specific to tendons, muscle, blood vessels, nerves, and bone.
This means that stem cell therapies can be the key to reducing pain, chronic inflammation, and the mitigation of many degenerative disease states.
At National Stem Cell Centers, our affiliated physicians utilize only adult stem cells harvested from your own fat tissue, without any form of artificial cellular manipulation. This means that our treatments are both effective and efficacious.
NeuraCell is a core facility that makes neural stem cell (NSC) research practical for those wishing to join the field. Our group has over 20 years of experience working with these cells and can now provide you with NSCs and everything you need to grow them. In addition to cells and media, we also provide a range of molecular tools including custom lentiviral shRNA and over-expression vectors. We also provide a consult based characterization service where we can assess how your products or reagents affect stem cell performance and behavior. A general list of services is provided below
Mr. Steven Lotz: Principal Investigator
Ms. Susan Goderie: Manager of Research
Mr. Shawn Sutton: Research Technician
Adult SVZ Neural Stem Cells
Any Age Embryonic stem cells from any region of the brain
Human Retinal Pigmented Epithelial cells
Neural Progenitor Cells (NPCs)
Media/ Dissociation Reagents
High-performance Media formulated according to optimal cell growth conditions.
Complete Defined Media for Neural Stem Cell Culture
Complete Defined Media for Human Retinal Pigmented Epithelial Culture
We can perform assays to verify how stem cell populations behave in response to certain environments, plastics, reagents, etc. Stem cell characterization is performed using trade secret assays via FACS and cell culture techniques. This can be used for neural stem cells as well as embryonic stem cells
Cell banking solutions shall ensure that their integrity is maintained and that a sufficient supply is readily available. Here we maintain a master and a working cell bank of high quality. We will also expand cells, harvest cells, generation the freezing medium and thaw cells to test performance.
Generation of custom lentiviral shRNA constructs
Generation of custom lentiviral over-expression constructs
Supply of NSC lines already expressing these shRNA or over-expression constructs
For details and pricing on NeuraCell offerings, please contact us firstname.lastname@example.org
The New York Stem Cell Treatment Center
Welcome to the New York Stem Cell Treatment Center. I am David Borenstein, MD, founder of the center, which is part of my practice, Manhattan Integrative Medicine.
Whether we are treating patients from New York City, Montreal or Toronto, we are dedicated to the advancement of quality care in the area of adult stem cell regenerative medicine. Our mission is to use advanced stem cell technology in order to improve the body’s ability to regenerate, heal and overcome a variety of inflammatory and degenerative conditions.
Stem Cell Therapy in New York, Toronto, and Montreal
Therapies are provided at our stem cell clinic for patients from all over the U.S. and around the world. Locations we serve include the surrounding areas of Manhattan, Brooklyn, Queens, the Bronx, Staten Island, Nassau County, Suffolk County, Long Island, Westchester, New Jersey, Connecticut, and Pennsylvania. We treat patients who visit us from Canada as well, from cities such as Montreal and Toronto.
Feel free to learn more about our stem cell treatments and our stem cell clinic. If you have further questions please go ahead and contact us, and if you would like to schedule an initial consultation, please fill out a candidate application.
Dr. David Borenstein, MD
Dr. David Borenstein obtained his medical degree from the Technion Faculty of Medicine in Haifa, Israel and completed his internship at Staten Island University Hospital. He has completed residencies at University Hospital at Stony Brook; Westchester County Medical Center; and St. Charles Hospital and Rehabilitation Center.
During the course of his career, he has attended numerous specialized training courses in order to expand the scope of his medical expertise that he uses every day at his stem cell treatment center. He is board-certified in Physical Medicine and Rehabilitation, certified in Medical Acupuncture, and is a member of numerous professional societies.
Dr. Borenstein has held many prestigious clinical appointments and positions in leading medical facilities. He has been published in the European Journal of Ultrasound and has been the Chief Investigator on a research project on Spinal Cord Injuries. He has conducted medical missions in North Korea, Ghana, Cuba, and other countries.
The Helen L. and Martin S. Kimmel Center for Stem Cell Biology
The Helen L. and Martin S. Kimmel Center for Stem Cell Biology was established in 2005 with a mission to be at the forefront of stem cell biology research. The goal is to conduct high caliber stem cell research that can ultimately lead to medical advances. We have over 40 faculty members, all of whom work on a variety of areas within stem cell biology. Members are affiliated with more than 20 different departments and institutions at the NYU Langone Medical Center, representative of the multidisciplinary nature of the center. The Kimmel Center for Stem Cell Biology faculty are internationally renowned and have received many honors and awards. Faculty include members of the National Academy of Sciences and Howard Hughes Medical Investigators.
Research at the center is focused on four broad areas, including (1) programming and reprogramming, lineage restriction and development, (2) tissue stem cells and disease, (3) regeneration and homeostasis, and (4) cancer and stem cells. Scientists within the center focus on one or more of the research areas and conduct their studies on a variety of tissue/organ systems ranging from embryonic stem cells to brain, heart, bone, lung and many more tissue systems in between.
The Stem Cell Biology training program in The Sackler Institute of Graduate Biomedical Sciences is designed to promote interdisciplinary studies within the field of stem cell biology for graduate students and postdoctoral fellows. We provide a great environment for trainees to explore the vast field of stem cell biology research. In addition to having a choice of mentors that range in their disciplines within stem cell biology, trainees are offered a seminar series, stem cell biology course, and stem cell biology tutorials, aimed at providing trainees with a breadth of knowledge in the field of stem cell biology. Our location in New York City also provides the opportunity for attendance at many local conferences and seminars within a short radius of the school.
The mission of the Helen L. and Martin S. Kimmel Center for Stem Cell Biology is to establish a world-class, multidisciplinary research center focusing on the basic biology of stem cells in a variety of species and cell types. Every day we are making strides towards achieving this goal!
PARK AVENUE STEM CELL THERAPY
Stem Cell Therapy is part of an exciting new field in medicine called Regenerative Medicine. In traditional medical treatment, we rely on NSAIDs, Steroids, other pharmaceuticals or surgery. At Park Avenue Stem Cell as part of the Cell Surgical Network(CSN), we are investigating the use of stromal vascular fraction(SVF) containing Adipose-Derived Stem Cells in the mitigation of cellular degenerative conditions such as chronic inflammation, arthritis, COPD, Alzheimer’s Disease and many other conditions. This research is part of an FDA approved preliminary safety study an IRB numbers ICSS-2016-001 though ICSS-2016-21, and we have maintained an extensive database that now includes more than 5000 patients. Please refer to “A Prospective Safety Study of Autologous Adipose-Derived Stromal Vascular Fraction Using a Specialized Surgical Processing System” by Mark Berman, M.D. and Elliot Lander, M.D., Am. J Cosmetic Surgery, 2017 for additional information.
PARK AVENUE STEM CELL OVERVIEW
#1 STEM CELL AUTHORITY
Dr. Joel Singer, a board-certified plastic surgeon, leverages over 30 years of extensive medical experience in his practices in New York City and Greenwich CT. Possessing a particular interest in nonsurgical and minimally invasive procedures, Dr. Joel Singer incorporates the latest techniques into his repertoire of services.
Dr. Singer began his formal education as an undergraduate at Queens College, The City University of New York. Committed to academic excellence, he was accepted into medical school after his second year of studying chemistry and biology. Dr. Singer earned his Doctor of Medicine from the Yale School of Medicine. He subsequently completed residencies at Yale-New Haven Medical Center and Rhode Island Brown University Hospital. He returned to academia in 2007, earning his M.B.A. from the George Washington University School of Business.
Dr. Singer has always been at the leading edge of innovation was the first plastic surgeon in Connecticut to perform liposuction in the early 1980s. His interest in fat transfer lead him to his current interest in investigating the benefits of autologous fat-derived Adult Stem Cells. He was an early affiliate in the Cell Surgical Network® an international organization of physicians devoted to clinical research of the benefits of adipose-derived stem cells.
He has built a physician network of multiple specialists who have been collaborating with Park Avenue Stem Cell to help treat chronic conditions in their patients. Dr. Singer is passionate about his research into the clinical applications of Stem Cells and has helped numerous people to be free of pain and chronic symptoms. Dr. Joel Singer has traveled around the globe to provide training to local plastic surgeons, as well as free surgeries to children in need. Dr. Joel Singer continues his involvement in the medical community through active participation in various medical organizations at both national and local levels, including the American Society of Plastic Surgeons and the New England Society of Plastic Surgeons.
Who is Dr. Soni
Named #1 Obesity Doctor in NY
Named America’s Top Physician 3 years in a row
Named Top Sleep Doctor in America 3 years in a row
Has 8 American Board Certifications
Using Knowledge of 8 Specialities for one aim: Weight Loss
Using knowledge of 8 specialties to find the root of the problems and not just treat the symptoms.
Our team is unique because
Dr. Soni is a board-certified physician in 8 different medical specialties
Over 25 years of experience
Most insurance plans are accepted
We offer a wide range of non-surgical options
Lipoplasty (liposuction) offered as a surgical option for abdominal (belly) fat removal
Medically supervised weight loss programs feature a 99% success rate
Weight loss programs covered by most insurance plans
Offer treatment for hormone imbalances and sexual disorders
Offer stem cell and PRP treatments
Specializes in sleep disorders
Comprehensive anti-aging treatments available
About our Practice
Liondale Medical is a private practice that focuses on the individualized care of our patients. We believe the best care comes from time spent listening to our patients. Dr. Bissoon sees a limited number of patients each day in order to ensure the quality of care we provide. Liondale Medical is committed to offering our patients personalized and comprehensive health care they want and deserve.
Dr. Lionel Bissoon
Dr. Lionel Bissoon; our medical director, has a background in Physical Medicine & Rehabilitation, Hormone Replacement Therapy, Cosmetic Dermatology and specializes in Regenerative and Restorative Medicine.
Dr. Bissoon is one of just a handful of doctors in the country who is employing the natural regenerative benefits of stem cells as an alternative to highly invasive joint replacement surgeries for patients with acute and chronic pain in their knees, shoulders, wrists, ankles, hands, feet, hips, elbows and certain spinal conditions. In addition, because stem cells can convert to from many tissues such as bone, cartilage, ligament, tendons, muscle or fat, they also can be used to treat debilitating conditions, such as degenerative arthritis, rheumatoid arthritis or osteoarthritis.
Dr. Bissoon has a well-known history of integrating new and innovative technology into the practice of medicine. In the late 1990’s he introduced Mesotherapy for the treatment of cellulite and weight loss. This procedure brought him numerous television, newspaper, and national magazine interviews.
Quality Medicine & Personally Tailored Programs
The use of a person’s own stem cells to heal themselves is a unique approach to treating Orthopedic, musculoskeletal and degenerative changes from arthritis. We are happy to offer this treatment to our patients who do not want to have surgery, improve their function and be pain-free.
Specializing in Regenerative Medicine
Liondale Medical continues to be at the forefront of cutting edge medical technology.
The use of stem cell therapy for joint injuries has been proven in most cases to eliminate the need for invasive reconstructive surgery, pain medications and improve function for people with joint and cartilage injuries.
The human body naturally contains millions of adult stem cells which are found in our fat, bones and other tissues. Adult stem cells can be harvested either from the patient’s, fat or bone marrow through a quick and relatively pain-free procedure. The stem cells are collected and injected within 30-60 minutes of the harvest into the site of the injury. The process of harvesting fat stem cells and bone stem cells are both FDA approved.
Adult stem cells are highly regenerative and have the ability to restore and repair injured tissue and joints, therefore, eliminating the need for invasive surgical procedures. Thus, there is no need to suffer needlessly, undergo invasive surgery, and take long term pain medications and non-steroidal medications if you are a candidate for the autologous stem cell treatment.
Is This Legal?
Yes! Currently, the FDA does not allow for manipulation and growing of stem cells; basically it is illegal. However, it is legal to administer the stem cells from fat and bone on the day of harvest. Plastic and Orthopedic surgeons have been using fat and bone marrow injections for decades. In summary, if stem cells are to be harvested from a person for medical purposes, they must be replanted in that person the same day without any cultivation or expansion.
STEM CELL SCIENCES, INC. (SCS) is a privately owned, NYSDOH licensed comprehensive stem cell bank, registered with the FDA and approved for the procurement, processing, storage, and distribution of human hematopoietic (blood-forming) stem cells of bone marrow and peripheral blood origin. Stem cells collected and processed by us have been successfully used since 1993 for the engraftment of many patients with a diagnosis of cancer (Acute and Chronic Leukemia, Lymphomas, both Hodgkin’s and Non-Hodgkin’s, Multiple Myeloma, Breast Cancer and other solid tumors) that were treated at several premier New York Hospitals.
In addition to its activity related to established therapeutic usage of hematopoietic stem cells for the treatment of cancer, the company is also engaged in bench research of marrow-derived mesenchymal (stromal/non-blood forming) stem cells for future clinical applications in the treatment of joint diseases as well as inflammatory bowel diseases and certain auto-immune disorders.
SCS facility is located in midtown Manhattan with an available space of approx. 3000 sq. ft. comprising an apheresis suite for peripheral blood stem cell collections, a stem cell laboratory, medical offices and examination rooms properly equipped to allow bone marrow aspiration sampling.
The stem cell laboratory hosts the necessary equipment for the large scale processing of stem cells under sterile conditions, short and long term in-vitro culture of stem cells, liquid nitrogen storage as well as microscopy and PCR capabilities for research purposes.
SCS intends to continue its excellence in banking hematopoietic stem cells for the treatment of certain cancers and to establish itself as a facility dedicated to advance marrow-derived stromal stem cell research in preparation for clinical applications.
Therapeutic usage of hematopoietic stem cells:
Transplantation of bone marrow and/or peripheral blood stem cells is currently used in conjunction with high dose chemotherapy for the intended curative treatment of certain blood disorders that include: Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Chronic Lymphocytic Leukemia (CLL), Hodgkin’s Disease (HD), several types of Non-Hodgkin’s Lymphoma (NHL) including Mantle Cell Lymphoma (MCL) and Multiple Myeloma (MM).
Transplantation for solid tumors is now considered experimental.
When the patient’s own stem cells are used, the transplant is called autologous and when a relative’s or unrelated donor’s stem cells are used, the procedure is called allogeneic transplantation. The latter is associated also with an immune component called graft-versus host disease that may have possible benefits for disease control, but may also cause complications leading to increased morbidity and mortality.
Adequate quality of stem cells is of paramount importance and is measured in both cell number content and presence of CD34 positive cells administered per kilogram body weight, in addition with proof that there is no bacterial, fungal or viral contamination of collections. Stem cell donors undergo a rigorous screening process including a detailed confidential questionnaire and blood testing for a variety of diseases.
We maintain stem cell collections for clinical use in liquid nitrogen storage.
2. Therapeutic usage of marrow-derived mesenchymal (stromal) stem cells:
These procedures are not yet in the main stream of practice of medicine, but rapid developments indicate that soon they may become a clinical reality in the United States. As such, transplantation of mesenchymal (stromal) stem cells is performed only under closely monitored clinical trials with FDA approval. The reason for such monitoring is due to the fact that several weeks of in-vitro culture are necessary to procure an adequate number of mesenchymal (stromal) stem cells and demonstration of mesenchymal (stromal) cells’ ability to differentiate into other types of cells (like cartilage or bone-forming) is necessary.
Under clinical trials (performed so far mainly overseas) mesenchymal (stromal) stem cells were found to be successful for the treatment of cartilage and bone defects associated with osteoarthritis and rheumatoid arthritis as well as in Inflammatory Bowel Diseases like Crohn’s Disease and Ulcerative Colitis or immune-related conditions like Graft-versus-Host Disease and Multiple Sclerosis.
Dr. Leon Reyfman and his team of pain management and relief specialists have always believed that the least invasive tactics for relieving pain are the most beneficial. When you visit Dr. Reyfman in his Brooklyn NYC office, you’re treated with respect and concern. If you’re in pain, it’s Dr. Leon Reyfman’s job to relieve it.
This therapy is widely becoming recognized and accepted throughout the traditional medical community as the first line of defense against chronic pain. Stem cell treatments rely on your own stem cells — removed from your bone marrow or adipose fat tissue and injected into the areas that are causing you pain. There’s no need to tread into the controversial field of embryonic stem cell cultivation when you carry all the necessary tools within your own body to heal yourself. When you visit the Brooklyn office, you never receive cookie-cutter treatment. Following a thorough medical history and a complete examination that may include blood work and X-rays, Dr. Leon Reyfman spends time getting to know you, your medical goals and your willingness to try innovative procedures, such as stem cell therapy.
Pain Is Not Your Friend
Chances are, you’re visiting an interventional pain management specialist because traditional means of treating your condition haven’t produced the results you want. To maintain your busy Brooklyn lifestyle, you can’t be slowed by degenerative conditions such as:
Chronic neck pain
Chronic back pain
Arthritis in your knee or ankle
These conditions often require you to undergo extensive replacement surgery that comes with lengthy recovery times. Even then, you still may have to deal with lingering pain. Surgery is sometimes the only answer, but it should be the very last option.
Injuries from athletics, accidents or persistent wear and tear can lead to other conditions that very often leave you feeling like you’re stuck with chronic pain for the rest of your life. These conditions include:
Rotator cuff tear
Foot and ankle injuries
Hand and wrist injuries
Natural Relief Is Available
As an interventional pain management specialist with years of experience in NYC, Dr. Leon Reyfman and his team have relied on traditional methods of pain management. But now they offer stem cell therapy treatment and regenerative therapy for all of the above-mentioned conditions … and more!
Additionally, platelet-rich plasma treatments rely on your own healthy blood cells to stir the recovery of diseased and damaged areas of your body. A simple centrifuge spins platelets out of your blood so that they can be injected directly into the places that need a greater blood supply.
Dr. Leon Reyfman’s Credentials
In the past, you may have been offered “alternative” or “natural” treatments from medical practitioners who practiced outside of mainstream medicine. That’s no longer true, as Dr. Leon Reyfman, MD, RPh, is both a medical doctor and a registered pharmacist. His credentials include:
Ross University Medical School’s prestigious Award of Academic Excellence
Internship in Internal Medicine at Maimonides Medical Center
Residency in Anesthesiology with focus on Pain Medicine at SUNY Downstate Medical Center in Brooklyn, NY
Fellowship at the world-renowned Columbia University College of Physicians and Surgeons/St. Luke’s Roosevelt Hospital
Board-certified through the American Board of Anesthesiology in both Anesthesiology and Pain Management
Dr. Leon Reyfman has extensive clinical experience and training in invasive and non-invasive pain management. He currently serves as the Director of Interventional Pain Medicine, and he is an Assistant Clinical Professor of Anesthesiology at SUNY Downstate Medical School. Dr. Reyfman is a member of the American Society of Interventional Pain Physicians and the International Spine Intervention Society.
Looking Out for Your Best Interests
Dr. Leon Reyfman is actively involved in pain management research; he’s seen first-hand the profound benefits that stem cell therapy has had on patients around the world. You may only need one or two visits before you begin to feel incredible relief from the debilitating pain you thought would never leave.
Thanks to his efforts and willingness to invest in the necessary technology, Dr. Reyfman, and his colleagues can provide you with access to life-altering treatments, such as:
Stem cell therapy for backs that can target disc degeneration, lumbar issues, bulging discs, herniated discs and more.
Stem cell therapy for shoulders, ideal for treating shoulder injuries, torn ligaments, osteoarthritis in the shoulder and rotator cuff injuries.
Stem cell therapy instead of knee replacement, a boon to seniors who face risky replacement surgery just to remain mobile.
Stem cell therapy for hips, another treatment that can eliminate the need for replacement surgery and painful physical therapy.
Regenerative Therapies Now Available
Instead of relying on addictive pain medications, steroid injections and risky surgery, talk to Dr. Leon Reyfman about whether you’re eligible for stem cell treatments and other regenerative therapies. While your age and general health come into play in the determination, you don’t have to worry about:
The risks of rejection, since the stem cells come from your own body
The medical expertise of your doctor, since Dr. Leon Reyfman has the training and experience
Through his numerous appointments and participation in cutting-edge research organizations, Dr. Reyfman stays abreast of the news. He’s an active member of many professional organizations, including:
American Medical Association (AMA), 2002–present
American Society of Anesthesiology (ASA), 2003–present
NY State Society of Anesthesiology (NYSSA), 2003–present
American Society of Regional Anesthesia and Pain Medicine (ASRA), 2005–present
American Society of Interventional Pain Physicians (ASIPP), 2007–present
International Spine Intervention Society (ISIS), 2007–present
North American Spine Society (NASS), 2011–present
The New York Pain Society, 2011-present — founding member
American Society of Addiction Medicine, 2010–present
The Medical Society of the State of New York, 2004–present
International Society of Medical Laser Application, 2013–present
His many licensures and certifications include:
Physician and Surgeon Licensed by the New York and New Jersey Medical Board
Board Certified by American Board of Anesthesiology
Diplomate of the American Board of Anesthesiology and Pain Medicine
Board Certified by American Board of Independent Medical Examiners
Fellow of Interventional Pain Practice