Mesenchymal Stem Cell Therapy For Feline Autoimmune Diseases
Stem cell therapies has great potential in treating a variety of illness and diseases in humans. What people may not realize is that stem cell treatments can also be beneficial to animals. Mesenchymal stem cell therapy is an intervention that is showing great promise in treating several autoimmune diseases in cats.
The Promise of Mesenchymal Stem Cell Therapy in Cats
In an article published this month in the Journal of Feline Medicine and Surgery, researchers reviewed the current and future potential of this emergent therapy in treating cats. These trials also help to gain better understanding of both the biology and immunology of mesenchymal stem cells.
Additionally, the review’s authors summarized the outcome of clinical trials that have investigated the use of mesenchymal stem cells in the treatment of a number of inflammatory and degenerative autoimmune related feline diseases. Traditionally, these diseases were treated by lifelong use of medications. However, these medications often have side effects and may not prevent the progression of these diseases.
What Feline Diseases Can Mesenchymal Stem Cell Therapy Treat?
One disease that mesenchymal stem cell treatment shows promise in treatment is feline gingivostomatitis. This oral disease is marked by severe and chronic inflammation of a cat’s gums as well as the tissue that lines the cat’s oral cavity. This form of gingivitis is diagnosed among cats with certain viral diseases, as well as bacterial infections and other nutritional and hormonal disorders.
With the use of mesenchymal stem cells, researchers noted this treatment was well-tolerated in affected cats and provided long-term relief in some cases.Mesenchymal stem cell therapy is also being investigated in the treatment of other feline diseases such as feline asthma, chronic enterotherapy, chronic kidney disease and ischemic acute kidney injuries among others.
While this emerging stem cell treatment shows potential, the authors of this review state that more research must be done. The authors stated in the review that mesenchymal stem cell treatments done with cats have not been able to produce the results that were seen in similar tests with rodents. Secondly, current studies on cats raise several logistical questions. These questions include the following:
- What is the ideal source of stem cells?
- What is the optimal route of administration?
- What impact does tissue donor status have on stem cell function?
What Are Mesenchymal Stem Cells?
Like most stem cells, mesenchymal stem cells are multipotent. This means they can produce more than one type of specialized cell of the body. Also known as MCS’s, these stem cells are found primarily in skeletal tissues but have the ability to differentiate into other cell types. Examples of these cell types include cartilage cells, bone cells as well as fat cells.
There is research that suggests that mesenchymal stem cells can differentiate to cell types found in other parts of the body. According to that research, MCS’s have the ability to differentiate into nerve cells, heart muscle cells, liver cells and endothelial cells, which form the inner layer of blood vessels.
Research into feline mesenchymal stem cells began in 2002 when they were first isolated from the bone marrow of cats. Later researchers were able to extract these cells from fat stores as well as amniotic membranes and fetal fluid. Additionally researchers discovered that feline MCS’s have similar immunomodulatory potency as more recently defined for human mesenchymal cells. However, the concentration of MCS’s in the bone marrow are much smaller than other stem cell types.
Despite the obstacles, authors of the review state that more research is being conducted on the efficacy of these stem cells in regenerative medicine. With more tangible results, mesenchymal stem cell treatments may be able to provide veterinarians with more tools in treating feline diseases.
Turn To Stem Cell Authority Today
As the science of stem cell therapy grows, so does the amount of treatment options. With stem cell therapy having the potential to treat a wide variety of human and animal diseases, you may want to know more about the benefits of stem cell therapy. The amount of hype surrounding stem cell treatments has created a certain amount of confusion regarding the authenticity of both knowledge and treatment options.
If you need further information about treatments such as mesenchymal stem cell therapy, call the professionals at Stem Cell Authority today. With many years of experience in the field, we are able to provide the best resources to better educate you about stem cell therapy. We also partner with the best stem cell facilities nationwide, and can help you find the treatment options that are the best fit for your needs.
Call Stem Cell Authority toll-free right now and learn more about the growing potential and power of stem cell therapy.